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Treating obesity and Type 2 diabetes using novel peptides derived from the venom of platypuses and echidnas.

Essentially

Researchers have created novel peptides from the venom of platypuses and echidnas to treat obesity and Type 2 diabetes, with reduced side effects.

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One of the world’s most important blood glucose lowering agents for treating diabetes is Exenatide. This glucagon-like peptide 1 (GLP-1) is derived from the saliva of the gila monster, a reptile found in the deserts of the southwest United States. Closer to home, a related GLP-1 hormone has been found in the venom of platypuses. Researchers have modified six novel peptides — currently being tested in vivo for efficacy in stimulating insulin production and suppressing appetite with reduced side effects.

Funded since: 2017

AusHealth partners: University of Adelaide, SAHMRI

Status: Pre-clinical studies underway.

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